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Filtered Search Results
Medchemexpress LLC Geniposidic acid | 27741-01-1 | 98.9% | 374.34 | 1 ML
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Geniposidic acid is an orally active FXR modulator and SIRT6 activator. It binds to specific sites on the FXR ligand-binding domain, driving nuclear translocation, coactivator recruitment, and transcription of downstream genes related to bile acid and cholesterol metabolism. It also improves metabolic dysfunction-related fatty liver disease by activating the SIRT6 signaling pathway.
- Inhibits inflammation.
- Modulates gut microbiota to alleviate colitis.
- Can be used in research on drug-induced liver injury.
- Applicable for inflammatory bowel disease research.
- Useful for metabolic dysfunction-related fatty liver disease studies.
- Suitable for research on metabolic dysfunction-related steatohepatitis.
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Matrix Scientific 2-IODOBENZOIC ACID-100G
2-Iodobenzoic acid, 98%; 100g,C7H5IO2, MFCD00002419, mw 248.02, [88-67-5]
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Medchemexpress LLC Neochebulagic acid | 28196-46-5 | 50 MG
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Neochebulagic acid is isolated from Phyllanthus emblica L.
- Purity of 96.71%
- Molecular weight of 972.68
- Chemical formula: C41H32O28
- Appearance: solid
- Color: white to off-white
- Classified as phenols, polyphenols
- Initial source: plants (Combretaceae, Terminalia chebula Retz.)
- Shipping at room temperature in continental US (may vary elsewhere)
- Storage at 4°C, protected from light; in solvent: -80°C for 6 months; -20°C for 1 month (protected from light)
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Medchemexpress LLC Isovanillic acid | 645-08-9 | 1 ML
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Isovanillic acid (3-Hydroxy-4-methoxybenzoic acid) is a phenolic acid isolated from Scrophularia ningpoensis. It exhibits anti-thrombotic activity by inhibiting fibrin and blood clot formation, prolonging partial thromboplastin time, and increasing platelet aggregation closure time. This compound also shows potential in research for insulin resistance and type 2 diabetes by increasing 2-[14C(U)]-deoxy-D-glucose uptake in LHCN-M2 cells.
- Phenolic acid isolated from Scrophularia ningpoensis.
- Exhibits anti-thrombotic activity.
- Potential for research in insulin resistance and type 2 diabetes.
- Slight uncompetitive inhibitory activity against thrombin.
- Inhibits fibrin clot and blood clot formation.
- Prolongs partial thromboplastin time.
- Increases closure time of platelet aggregation.
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Medchemexpress LLC Diffractaic acid | 436-32-8 | MFCD00078235 | 5 MG
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Diffractaic acid, a major constituent of *U. longissimi*, acts as an effective proapoptotic agent in various disorders research. It is also the analgesic and antipyretic component of *Usnea diffracta*.
- Antiproliferative activity against human HaCaT cells (IC50 = 2.6 μM)
- Inhibition of LTB4 biosynthesis in A-23187-stimulated bovine PMNL cells (IC50 = 8 μM)
- Shows an analgesic effect in mice by acetic acid-induced writhing and tail-pressure methods
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Medchemexpress LLC Lawsone | 83-72-7 | 50 G
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Lawsone is an orally active naphthoquinone dye isolated from the leaves of *Lawsonia inermis*. It is utilized in anti-tumor drug research and exhibits antibacterial, antitumor, and antioxidant activities, as well as inducing apoptosis.
- Orally active naphthoquinone dye
- Isolated from the leaves of *Lawsonia inermis*
- Induces apoptosis
- Exhibits antibacterial activity
- Exhibits antitumor activity
- Exhibits antioxidant activities
- Used in anti-tumor drug research
- Solid appearance
- Light yellow to yellow color
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Selleck Chemical LLC PF-562271 HCl
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PF-562271 HCl is the hydrochloride salt of PF-562271 which is a potent ATP-competitive reversible inhibitor of FAK with IC50 of 1 5 nM 10-fold less potent for Pyk2 than FAK and 100-fold selectivity against other protein kinases except for some CDKs Phase 1
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Selleck Chemical LLC PTP Inhibitor I S3696-25mg
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PTP Inhibitor I is a cell-permeable protein tyrosine phosphatase (PTP) inhibitor with Ki values of 43 and 42 M for SHP-1( SH2) and PTP1B respectively
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Medchemexpress LLC Chebulic acid | 23725-05-5 | 1 MG
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Chebulic acid is a phenolic acid compound isolated from the plant *Terminalia chebula*, recognized for its strong antioxidant properties. It functions by disrupting protein cross-links caused by advanced glycation end products (AGEs) and preventing the formation of new AGEs. This compound has demonstrated effectiveness in addressing elevated metabolic parameters, oxidative stress, and liver damage, indicating its potential therapeutic role in conditions such as asthma, diabetes, and for general liver protection. It is intended for research use only.
- Potent antioxidant activity
- Disrupts and inhibits advanced glycation end products (AGEs)
- Effective in managing elevated metabolic parameters
- Reduces oxidative stress
- Supports liver health and protection
- Potential therapeutic agent for asthma and diabetes research
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000656432 ENDOTHELIN-2 49-69 1MG
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Cayman Chemical CAY10494 Pharmaceuticals and I
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A synthetic intermediate useful for pharmaceutical synthesis
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Cayman Chemical PtdIns 4 5P2 1 2dipalmitoyl
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A synthetic analog of natural PtdIns featuring C16:0 fatty acids at the sn-1 and sn-2 positions; contains the same inositol and DAG stereochemistry as the natural compound
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Medchemexpress LLC Benzoic acid, 4-hydroxy-3,5-dimethoxy- | 530-57-4 | 99.9% | 198.17 | 1 G
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Syringic acid is correlated with high antioxidant activity and inhibition of LDL oxidation.
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Medchemexpress LLC ω-Muricholic acid | 6830-03-1 | MFCD11142482 | ≥99.0% | 408.57 g/mol | C24H40O5 | 1MG
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ω-Muricholic acid (ω-MCA) is a murine-specific secondary bile acid supplied as a high-purity analytical reagent for biochemical and metabolic research. It is used in studies of bile acid metabolism, microbiome-host interactions, and metabolite profiling. Molecular formula C24H40O5, molecular weight 408.57 g/mol. Supplied for in vitro and analytical workflows; for research use only.
- High-purity analytical standard for metabolite profiling.
- Relevant to studies of bile acid metabolism and metabolic disease.
- Molecular formula C24H40O5 and molecular weight 408.57 g/mol.
- Offered in small, accurately measured quantities for analytical use.
- For research use only; not for human or veterinary use.
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Medchemexpress LLC Benzoic acid, 4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]- | 119-24-4 | 98.1% | C14H12N6O3 | 10 G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Pteroic acid is a precursor to significant compounds like Folic acid and Vitamin B12. It facilitates the examination of how different compounds influence cell growth and development. This product is for research use only and not sold to patients.
- Precursor to Folic acid and Vitamin B12
- Facilitates examination of how compounds influence cell growth and development
- Exhibits inhibitory activity against CDK4 complex in Sf9 cells
- Enhances activity of partially purified beef liver folylpolyglutamate synthetase (FPGS)
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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